In this study, mHapSuite and mHapSc were developped by Yuyang Hong. Integrative data analysis was performed by Zhiqiang Zhang.
Identification of DNA methylation haplotype blocks (MHBs) in cancers. Code
Cancer MHBs are enriched in accessible chromatin regions. Code
Cancer MHBs are associated with dysregulation of gene expression. Code
Validation of cancer MHBs and their associated regulatory role using single-cell data. Code
Cancer MHBs are associated with differentially expressed genes in pan-cancer. Code
Characterization of aging-associated MHBs in precancerous lesions. Code