Reproducible code

In this study, mHapSuite and mHapSc were developped by Yuyang Hong. Integrative data analysis was performed by Zhiqiang Zhang.

Scripts

Figure 1

Identification of DNA methylation haplotype blocks (MHBs) in cancers. Code

Figure 2

Cancer MHBs are enriched in accessible chromatin regions. Code

Figure 3

Cancer MHBs are associated with dysregulation of gene expression. Code

Figure 4

Validation of cancer MHBs and their associated regulatory role using single-cell data. Code

Figure 5

Cancer MHBs are associated with differentially expressed genes in pan-cancer. Code

Figure 6

Characterization of aging-associated MHBs in precancerous lesions. Code